Nebido – administration

Nebido is a long-acting injectable form of testosterone undecanoate, used in hormone replacement therapy for individuals with low testosterone levels, including transgender men and individuals with hypogonadism. Here’s more detailed information about Nebido, focusing on dosage and administration:


  • Preparation:
    • Before administering Nebido, ensure that you have the correct dosage prescribed by your healthcare provider.
    • Wash your hands thoroughly with soap and water to minimize the risk of infection.
    • Gather all necessary supplies, including the Nebido vial, a syringe, a sterile needle, alcohol swabs, and a sharps container for safe disposal of needles and syringes.
  • Injection Site Selection:
    • Nebido is typically administered via intramuscular injection into the gluteal muscle (buttocks).
    • Choose an appropriate injection site and clean the area with an alcohol swab to disinfect the skin and reduce the risk of infection.
  • Injection Technique:
    • Remove the protective cap from the needle and attach it to the syringe.
    • Draw up the entire contents of the Nebido vial into the syringe. Nebido is usually provided in pre-filled syringes for convenience.
    • Hold the syringe with one hand and use the other hand to stretch or tense the skin around the injection site.
    • Insert the needle into the muscle tissue at a 90-degree angle with a quick, smooth motion. Aim to penetrate the muscle belly rather than the surrounding fatty tissue.
    • Once the needle is fully inserted, slowly push the plunger down to inject the medication into the muscle.
    • After the injection is complete, withdraw the needle at the same angle it was inserted, and immediately apply gentle pressure to the injection site with a clean cotton ball or gauze pad to minimize bleeding.
  • Post-Injection Care:
    • Dispose of used needles and syringes in a sharps container according to local regulations.
    • Monitor the injection site for any signs of infection, such as redness, swelling, or warmth, and report any unusual symptoms to your healthcare provider.
    • It’s normal to experience some mild discomfort or soreness at the injection site, but severe pain or persistent symptoms should be evaluated by a healthcare professional.

General Considerations:

  • Nebido injections should be administered by a healthcare professional or under their supervision.
  • Follow all instructions provided by your healthcare provider regarding dosage, administration, and monitoring.
  • Regular monitoring of hormone levels and follow-up appointments are essential to evaluate treatment effectiveness and adjust the dosage if necessary.

If you have any questions or concerns about your Nebido therapy, be sure to discuss them with your healthcare provider. They can provide personalized guidance and support to ensure safe and effective treatment outcomes.

Updated on February 16, 2024

Was this article helpful?

Related Articles

Request an article
If you would like some knowledge added to our knowledge base, send your suggestions here.
Request Knowledge