Testosterone Injections

Summary of the different types of testosterone injections available for gender-affirming hormone therapy:

Testosterone TypeAdministration MethodFrequencySelf-AdministrationCost Range (Approx.)Notes
Sustanon (Testosterone Isocaproate)Intramuscular injectionEvery 2-4 weeksYes (after training)£8 – £25 per ampoule– Contains four testosterone esters
Not suitable for those with peanut or soya allergies
– Peak levels reached within 24-48 hrs
Nebido (Testosterone Undecanoate)Intramuscular injectionEvery 10-14 weeksNo (requires healthcare professional)£110 – £120 per ampoule– Slow release, maintaining stable levels
– Not for self-administration
Testosterone EnantateIntramuscular or subcutaneous injectionEvery 1-2 weeksYes (after training)£105 – £130 per 3 ampules– Suitable for self-administration
– Consistent levels maintained
Testosterone CypionateIntramuscular or subcutaneous injectionEvery 1-2 weeksYes (after training)Similar to Testosterone Enantate– Similar administration and frequency to Enantate
– Common in the US
Testosterone Injections

Additional Information:

  • Commencing: If you are commencing testosterone for the first time and want to go straight to injections, it is generally fine to commence straight away with injections. There is no need to begin with testosterone gel before switching to injections.
  • Monitoring: Regardless of the type, testosterone levels should be monitored during treatment, particularly at the end of an injection interval. Adjustments to the injection interval may be needed based on testosterone levels.
  • Availability: Availability and cost will vary based on location and healthcare systems.
  • Cautions: Note that Sustanon contains arachis oil, and so is not suitable for people with allergies to peanuts or soya.
  • Patient Information Leaflet (PIL): Always refer to the PIL for detailed information about administration, contraindications, and possible side effects.

This table provides a general overview and may not cover all specifics or individual variations in therapy. It’s essential to consult with a specialist provider for personalised advice and instructions.

Updated on March 7, 2024

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