Unwanted Effects of Testosterone

The table below lists the known side effects, but some of these effects may actually be the desired therapeutic effects in certain medical contexts.

It’s important to understand that people can have varying responses to medications, and what one person experiences may differ from another. If a specific side effect is not listed, it’s less likely to be directly caused by the medication, but this does not rule out the possibility entirely.

In cases where you suspect a medication may be causing an unwanted effect, adjusting the medication, trying an alternative treatment, or discontinuing the medication can help clarify whether the side effect is medication-related or has another underlying cause.

Side Effects
Very Common (> 10%)
– Accelerated Growth
– Application Site Pruritus / Itching (Up To 37%)
– Itching
– Allergic Contact Dermatitis (Up To 37%)
Common (1%-10%)
– Acne
– Induration
– Burning
– Back Pain
– Hemarthrosis (Bleeding in the Joint)
– Diarrhea
– Oily Stools (Due To IM Injection Oily Solvent)
– Acid Reflux
– Gastrointestinal Bleeding
– Gum Or Mouth Irritation (9.2%)
– Taste Bitter
– Gum Pain
– Gum Tenderness
– Gum Edema / Swelling
– Funny Taste
– Tiredness
– Sweating
– Chills
– Body Pain
– Odd Smell
– Headache
– Vertigo (Topical Testosterone)
– Hot Flush
– Hypertension / High Blood Pressure
– Increased Estradiol Levels
– Injection Site Pain
– Injection Site Discomfort
– Injection Site Pruritus / Itching
– Erythema
– Injection Site Hematoma
– Injection Site Irritation
– Injection Site Inflammation
– Injection Site Reaction
– Application Site Erythema
– Application Site Warmth
– Application Site Irritation
– Application Site Vesicles
– Application Site Exfoliation
– Application Site Burning
– Application Site Induration
– Bullae At Application Site
– Mechanical Irritation At Application Site
– Rash At Application Site
– Contamination Of Application Site
– Irritability
– Insomnia
– Mood Swings
– Aggression
– Polycythemia
– Hematocrit Increased
– Sinusitis
– Nasopharyngitis
– Bronchitis
– Weight Increased
– Appetite Increased
– Fluid Retention
Uncommon (0.1%-1%)
– Abnormal Liver Tests
– Increased AST Liver Enzyme
– Alopecia / Hair Loss
– Erythema
– Rashes
– Pruritus / Itching
– Dry Skin
– Folliculitis (Testosterone Topical)
– Arthralgia (Joint Pains)
– Pain In Extremity
– Muscle Spasm
– Muscle Strain
– Myalgia (Muscle Pains)
– Musculoskeletal Stiffness
– Increased Creatine Phosphokinase
– Increased Estradiol
– Increased Testosterone
– Asthenia / Weakness
– Night Sweats
– Cardiovascular Disorder
– Cough
– Dyspnea / Trouble Breathing
– Snoring
– Dysphonia
– Depression
– Emotional Disorder
– Restlessness
– Increased Libido
– Decreased Libido
– Allergic Reactions
– Increased Glycosylated Hemoglobin
– Hypercholesterolemia
– Increased Triglyceride
– Increased Red Blood Cell Count
– Increased Hemoglobin
– Prolonged Activated Partial Thromboplastin Time
– Prolonged Prothrombin Time
– Migraine
– Tremor
– Dizziness
– Nausea
– Decreased Urine Flow
– Urinary Retention
– Urinary Tract Disorder
– Nocturia / Peeing at Night / Peeing at Night
– Dysuria / Painful Urination
– More Tears
Rare (< 0.1%)
– Abdominal / Stomach Pain
– Abnormal Liver Function
– Fever
– Malaise / Feeling Unwell
– Urination Disorders
Updated on February 6, 2024

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